Dendritic cell in chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) is an airway disorder characterized by airway obstructions that are not fully reversible. The main cause of COPD is cigarette smoking; however, not all smokers are susceptible, as immunological responses have a major role in the development of the disease. In particular, dendritic cells (DCs) play an important role in the development of COPD; however, their role is still not fully understood. In this booklet I am highlighting the possible role of DCs in the disease progress in studies that used human, animal or cell culture models.